SARS-CoV-2

The global increase in the viral population size (M(t), at time t) and the mutation accumulation (R(t)) may have indeed triggered the runaway evolution in late 2020, leading to the highly evolved Alpha and then Delta strain.

In the spread of SARS-CoV-2, there have been five waves of replacement between strains, each of which having a distinct set of mutations. The first wave is a group of 4 mutations (C241T, C3037T, C14408T, and A23403G [this being the amino acid change D614G]) has twin-beginnings.

Project on the evolution of SARS-CoV-2, including origin, transmission, adaptive evolution, etc.